Proactive Investors
28 Sept 2026, 07:04 UTC · 2h ago
Verdict
Headline takes no side. We score COIL +0.60 across four claims — strongly bullish.
+0.60strongly bullish
More positive than 77% of ticker scores this week
What the story claims
4 claims · scored −1 bearish … +1 bullish · 2 new · 2 priced in
Coiled Therapeutics expects to report the first safety and pharmacokinetic data from its new AO-252 formulation by the end of 2026.
Newpublished Sep 28 2026
So whatPositive results in Q4 2026 would trigger the next catalyst: a safety database of 50 patients in 2027.
More positive than 93% of claims this week
The company plans to dose up to 30 patients with the new softgel formulation of AO-252 this year.
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Newpublished Sep 28 2026
So whatScaling from the 6 currently enrolled patients to 30 represents a 5x increase in the immediate test population.
More positive than 79% of claims this week
Coiled raised £8.5 million through a placing and subscriptions to fund development through 2026 and 2027.
Priced inreported for six months to June
So whatThis capital provides a runway through FY2027, reducing the immediate risk of dilutive financing before the 2027 efficacy data.
More positive than 54% of claims this week
In April, 80% of patients on twice-daily dosing of AO-252 saw tumours stabilise or shrink.
Priced inreported in April
So whatThe 40% differential between twice-daily and once-daily dosing justifies the current focus on the 120mg twice-daily softgel group.
More positive than 54% of claims this week
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