PRNewsWire
08 Jun 2026, 00:10 UTC · 14h ago
Story key points
3 claims · impact-rated
ASC30 Phase II results showed dose-dependent weight reductions up to 7.7% at 13 weeks with a better GI tolerability profile than orforglipron. — Positive Phase II human data and a superior safety profile compared to a known competitor (OFG) significantly derisk the lead candidate.
+0.60ASC30 demonstrated 2- to 3-fold greater potency and 5-fold higher oral exposure than orforglipron in in vitro and non-human primate studies. — Stronger pharmacological potency suggests a competitive edge in the crowded oral GLP-1 market.
+0.40Preclinical data for ASC39 showed a 9.9% body weight reduction in rat models and high selectivity for the amylin type 1 receptor. — Positive early-stage data expands the company's obesity pipeline, though preclinical results are less predictive than human trials.
+0.30Ticker attribution
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The company presented positive clinical and preclinical data for its obesity drug candidates ASC30, ASC37, and ASC39.
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